The Leishmania parasite, which causes the human disease leishmaniasis, acts as a probiotic in the insect that transmits it to humans, protecting them from bacterial disease, research shows. Around 12 million people are currently infected with Leishmaniasis worldwide, mostly in South America, Africa and Asia. It is estimated to kill 20-50,000 people per year. Sandflies transmit the parasite by feeding on an infected mammal and, if they survive long enough, feeding on another mammal, and passing the parasite on to them.
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